Best vertical mouse 2024: reduce wrist strain and pain with these top choices

The best vertical mouse for most people 

Wireless: Yes
Ambidextrous: Yes
Weight: 90.g

While it's not cheap and not pretty, when it comes to performance there's nothing lacking with this mouse. It's useable both left and right-handed and has customisable DPI with four settings from 500 all the way up to 2,000. Rapid charging can give you two hours of use from just 30 seconds too so there's no excuse to go without. 

The best premium vertical mouse

Wireless: Yes
Ambidextrous: Yes
Weight: 149g

Yes, it's the most expensive model on this list but you get what you pay for. It has a staggering 30 days use on a single charge and has a supreme level of adjustment to cater to your hands and reduce the risk of RSI. You can use it from completely vertical to a horizontal handshake style, so there are no excuses for discomfort. 

The best budget vertical mouse 

Wireless: Yes
Ambidextrous: Yes
Weight: 385.55g

If you're looking for something a little unusual, the Posturite Penguin Ambidextrous Wireless Ergonomic Mouse is it: besides being suitable for left and right handers, it actually looks a bit like a penguin. The DPI goes all the way up to 1,200 and features a battery life of 30 days between charges.

The best vertical gaming mouse 

Wireless: No
Ambidextrous: No
Weight: 175g

Vertical mice and gaming mice don't often cross paths because they're usually catering to different groups of people, but the Speedlink Sovos is an affordable effort with RGB lighting to boot. The specs don't match up with the very best gaming mice out there and It's wired only but if you're in a long gaming session you'll appreciate the vertical shape. 

The best vertical mouse for left handers

Wireless: No
Ambidextrous: No (Left only)
Weight: 100g

If you're a lefty (no shame) then this is the vertical mouse for you. Made speciffically for left-handers, there are wireless versions of the E9 but they are much more expensive and fuctionally near identical. It's precise enough for office work, and with two buttons for dedicated internet navigation. Its dpi can be set to 800, 1200,1600 or 2400. 

Best affordable option  for right handers

Wireless: No
Ambidextrous: No
Weight: 128g

If you're a right hander and don't want to spend much on a vertical mouse, then this Anker model is a great choice. Despite its low price, mind, you get a vertical mouse that delivers a 1600DPI sensor, six button setup.

Best 'handshake' vertical mouse

Wireless: Yes
Ambidextrous: No
Weight: 189g

Sporting a high profile shape and curved thumb rest, the Evoluent comes with six programmable buttons, which is perfect if you do a job of a repetitive nature. Your hands will have never been so comfy. This is the wireless model too, but it doesn't suit left handers.

Best vertical mouse for Windows fans

Wireless: Yes
Ambidextrous: No
Weight: 380g

The Sculpt is an ergonomic design that uses just enough height and width to fit the natural contours of your hand. The thumb scoop on the side enables you to grip naturally. You can customise the Windows Button on top while the back button next to it offers the ability to navigate much faster without extra strain too. 

Best long lasting vertical mouse

Wireless: Yes
Ambidextrous: No
Weight: 135g

With 4 months on a full charge or 3 hours from a 1 minute charge, the LogitechMX Vertical Mouse is a master of endurance. It features advanced optical tracking with a 4,000 DPI high-precision sensor. The clever cursor speed switch instantly adjusts DPI speed and accuracy. You can pair three devices and switch between them easily.