Sqaure Enix has registered a trademark for an IP called simply Deus Ex: Defiance, which may be the sequel to Deus Ex: Human Revolution
Deus Ex: Human Revolution, the prequel to the critically lauded and groundbreaking cyberpunk first-person adventure classic Deus Ex, was one of the better games of 2011, and its sales pretty much guarantee a second installment. Now, it seems that one may already be in the works
Square Enix has filed a trademark for an IP for something called Deus Ex: Defiance. What this IP is, at this stage, isn't completely clear. It could be a sequel to the 2011 entry or a touchscreen app. It could even be the name for the much touted Deus Ex movie tie-in that is currently in the works with Scott Derrickson - the director of Sinister and The Exorcism Of Emily Rose - helming it.
Given the widespread critical praise for Deus Ex: Human Revolution, to say nothing of its impressive sales, which topped 2m units in the US and Europe, it's more than likely Deus Ex: Defiance is a follow up. Square Enix is holding to its position of not commenting "on rumour and speculation" for now.